GMP Compliant Ph.D. Led R&D Global Exporter

China Top Probiotic Ingredients Manufacturer & Exporter

High-Activity, Clinically-Documented Probiotic Strains & Functional Ingredients Custom-Engineered for Global Food, Nutraceutical, and Therapeutic Sectors.

Premium Active Ingredients & Bio-Solutions

Explore our high-purity raw materials and functional ingredients engineered for stability, bio-efficacy, and targeted wellness solutions.

Wholesale Factory Price Food Grade Chill Extract 10% Oleoresin Of Capsicum
Wholesale Factory Price Food Grade Chill Extract 10% Oleoresin Of Capsicum
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Feed Grade 99% Amino Acid Manufacturer Price 25Kg Dl-methionine Powder for Poultry
Feed Grade 99% Amino Acid Manufacturer Price 25Kg Dl-methionine Powder for Poultry
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Cosmetic Grade Skin Care Antioxidant Preservative Raw Material 4-Hydroxyacetophenone
Cosmetic Grade Skin Care Antioxidant Preservative Raw Material 4-Hydroxyacetophenone
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Multi-Color Industrial Grade Inorganic Iron Oxide Pigment Powder
Multi-Color Industrial Grade Inorganic Iron Oxide Pigment Powder Red Yellow Green Blue Black For Ceramic Glaze Coating Pigment
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YiHao Top Purity Bacillus Subtilis Probiotics Powder
YiHao Top Purity Bacillus Subtilis Probiotics Powder High Quality Light Tan ISO Certified Feed Grade Enhances Immunity Shrimp
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Pediococcus Acidilactici Food Ingredients From China
Pediococcus Acidilactici Food Ingredients From China Freeze-dried Probiotics Powder Original Manufacturer 10 Billion 100 Billion
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Instant Soluble Corn Maltodextrin DE 18-20 Food Grade
Instant Soluble Corn Maltodextrin DE 18-20 Food Grade 25kg Caili Brand for Beverage and Sports Nutrition Energy Drink Mix
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Natural Water Soluble Taro Flavor Solid Drink Powder
Natural Water Soluble Taro Flavor Solid Drink Powder OEM Private Label Bubble Tea Ingredient
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About Shaanxi Diaries Biotech Co., Ltd.

A trusted global titan in biotech innovation, plant extractions, and standardized probiotic cultivation.

Shaanxi Diaries Biotech Co., Ltd. is a modern high-tech enterprise specializing in the research and development, production, and global distribution of plant extracts, natural raw materials, and functional ingredients for the health, food, and cosmetic industries.

With strong technical expertise and advanced manufacturing capabilities, the company is committed to providing high-quality, safe, and effective natural solutions to customers worldwide. Our products are widely used in dietary supplements, functional foods and beverages, cosmetics, personal care products, animal nutrition, and agricultural applications.

Over the years, Shaanxi Diaries Biotech has built long-term partnerships with more than 5,000 companies across over 80 countries and regions, earning a strong reputation for reliability, consistency, and innovation in the natural ingredients industry.

Our Main Products Include: Plant extract powders, standardized herbal extracts, fruit and vegetable powders, botanical raw materials, and customized functional ingredient solutions tailored to customer requirements.

We also provide professional OEM/ODM services, including formulation support, product development, and private label manufacturing to meet diverse market needs. By maintaining strict microbiological control and biological assays, we ensure that every batch of probiotic strains meets the absolute peak of cell viability and gastrointestinal passage survival.

Global Footprint & Production Capability

Delivering biological stability and active cell density on an industrial scale.

70,000+
Sqm Production Base
6
Advanced Extraction Lines
80+
Exporting Countries
5,000+
B2B Global Partners

Probiotic Technical Blueprint & Stabilization Milestones

How Shaanxi Diaries Biotech solves the critical challenge of cell viability and metabolic activity.

The industrial applicability of probiotics hinges on a singular parameter: active cell survival rate from factory packaging to customer consumption. Probiotic ingredients are highly sensitive to thermal gradients, mechanical shear stress, relative humidity ($a_w$), and gastric acidity. At Shaanxi Diaries Biotech, our Ph.D.-led engineering team has designed a multi-layer stabilization system to address these thermodynamic and physiological bottlenecks.

Advanced Cryoprotectant Matrix

Using a proprietary blend of disaccharides and antioxidant polymers, we form an amorphous glassy matrix around cell membranes during freeze-drying. This prevents the crystallization of intracellular water, eliminating structural shearing of Lactobacilli and Bifidobacteria membranes.

Microencapsulation Technology

For applications exposing bacteria to extreme heat (like tablets or animal feed pelleting), we apply a lipid and alginate coating. This micro-shield preserves strain viability under thermal loads of up to 85°C and prevents gastric juice degradation.

Low Water Activity ($a_w$) Processing

We operate cleanrooms at a strict relative humidity level of <20%. By driving final product water activity ($a_w$) below 0.15, we halt cellular respiration, extending product shelf life to 24 months under ambient conditions.

Macro-Industry Applications & Targeted Formulations

Custom probiotic solutions engineered to yield high-efficacy clinical outcomes across market segments.

Target Segment Specific Challenges Addressed Recommended Strains / Raw Materials Key Efficacy Metrics
Human Dietary Supplements Gastric passage survival, shelf-life without refrigeration, high density counts. Lactobacillus acidophilus, Bifidobacterium animalis subsp. lactis, Urolithin A 98% >100 Billion CFU/g stable at 25°C, targeted gut mucosal colonization.
Functional Beverage & Foods Thermodynamic processing stability, soluble mixing kinetics. Bacillus coagulans, Pediococcus acidilactici, Corn Maltodextrin DE 18-20 Survivability in pasteurized liquids, consistent dispersion index.
Animal Health & Aquaculture High temperature pelleting (up to 85°C), low pH stability in monogastric animals. YiHao Bacillus subtilis Powder, Feed Grade DL-Methionine Rapid competitive exclusion of pathogens, improvement in feed conversion ratio (FCR).
Nutraceutical Cosmetics Antioxidant stability, preservation inhibition without synthetic chemical agents. 4-Hydroxyacetophenone, Yeast Protein Hydrolysate Restoration of skin microbiome flora, safe preservation, radical scavenging.

China Factory 4.0: Supply Chain Resilience & Extraction Excellence

Tour our state-of-the-art facility in Xi'an, Shaanxi Province, equipped with modern GMP automation.

Our production base spans over 70,000 square meters, utilizing six advanced plant extraction production lines and fine extraction workshops. Operating under strict GMP-compliant systems, we maintain automated raw material processing, high-throughput extraction, and cleanroom packaging to prevent cross-contamination.

Materials Mixing facility at Shaanxi Diaries Biotech
Materials Mixing
Automatic Filling line
Automatic Filling
Packaging Operations
Packaging
Secondary Packaging and QA check
Packaging
Automated Filling Machine
Filling Machine
High speed Packaging Machine
Packaging Machine
Automatic Mixing Machine
Automatic Mixing Machine
Pure Water Machine
Pure Water Machine
Boiler Room / Energy Station
Boiler
Concentrated Extracting Tank
Extracting Tank
Low Temperature Concentration Equipment
Concentration Equipment

Global Procurement, Supply Chain Resilience & Compliance

Fulfilling rigorous global verification requirements for large-scale operations.

Complete Certification Hierarchy

Quality assurance is not a checklist; it is the cornerstone of our manufacturing design. Shaanxi Diaries Biotech operates under strict international regulatory compliance frameworks, assuring product identity, safety, and traceability. Our certifications include:

  • HACCP & ISO22000: Complete biological risk assessment and preventive control protocols.
  • Kosher & Halal: Full validation of raw material purity and strict equipment cleaning steps.
  • Organic Compliance: Certified USDA Organic and EU Organic for select botanical ingredients.
  • FDA Compliance: Regular facility audits and registration to ensure frictionless cross-border customs entry.

Procurement Pipeline & Logistics

Navigating international shipping timelines requires robust planning. We provide global supply chain resilience through:

  • Microbiological Assay: Every batch is accompanied by a Certificate of Analysis (COA) specifying strain CFU counts, heavy metal limits, and pesticide residue profiles.
  • Temperature-Controlled Shipping: Cold-chain maritime and air freight options to preserve strain viability in trans-continental transit.
  • OEM Customization: Formulations can be delivered in bulk powder, customized blends, capsule encapsulation, or custom-label retail packaging.

R&D Roadmap & Next-Generation Biotics

Advancing the science of microbiome optimization through biotechnology.

The next phase of microbiome science is shifting towards precision therapeutics. Shaanxi Diaries Biotech is heavily investing in clinical validation and isolation of novel strains targeting the Gut-Brain Axis, Metabolic Homeostasis, and Immunological Modulation. Our current R&D pipeline is focused on three primary areas:

  1. Postbiotics (Cell-Free Supernatants): Developing heat-stable, non-viable bacterial by-products (metabolites, peptidoglycan, and teichoic acids) that deliver predictable physiological benefits without the packaging and formulation challenges associated with live bacteria.
  2. Synbiotic Matrices: Structuring combined probiotic and prebiotic formulations. By matching prebiotic fibers (such as inulin and FOS) with specific strain enzymes, we accelerate gut colonization and colonization velocity in human and animal digestive systems.
  3. Next-Generation Sequencing (NGS) Identification: Utilizing metagenomic sequencing platforms to verify taxonomic identity at the strain level, guaranteeing absolute genetic purity and preventing contamination throughout the expansion cycle.

Frequently Asked Technical & Commercial Questions

Direct answers for purchasing teams, quality assurance directors, and formulation engineers.

What is the standard cell count (CFU/g) of your probiotic ingredients?

Our freeze-dried powders are standardly available in concentrations ranging from 10 Billion (1.0 x 10^10) to 100 Billion (1.0 x 10^11) CFU/g. We also manufacture super-concentrated formulations reaching up to 400 Billion CFU/g for select strains like Bacillus coagulans and Lactobacillus rhamnosus.

How do you guarantee the survival of probiotics during transport?

For sensitive strains, we pack our products in triple-laminated aluminum foil bags with moisture absorbers, shipped in heavy-duty styrofoam coolers containing gel dry-ice packs. We closely monitor seasonal temperatures along transit paths and utilize express air freight to ensure the shipment reaches your facility within safe thermal parameters.

Are your probiotic strains safe for aquaculture and livestock feed processing?

Yes, our strains like Bacillus subtilis and Pediococcus acidilactici are specifically selected and certified as feed-grade. These spore-forming and microencapsulated strains are highly resilient against thermal mechanical friction during feed extrusion and pelleting, maintaining effective CFU counts in the finished animal feed.

Do you support customized strain blends and private labeling (OEM)?

We provide full-service OEM and contract manufacturing options. This includes blending multiple strains, adding functional plant extracts, formatting into oral capsules, tablets, or sachets, and packaging them under your brand with complete regulatory documentation support.

Diverse Bio-Chemical & Amino Acid Solutions

Broaden your product range with our validated bulk ingredients for sports, cosmetics, and agricultural applications.

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